Ocular penetration and anti-inflammatory activity of ketorolac 0.45% and bromfenac 0.09% against lipopolysaccharide-induced inflammation.

Waterbury, L David; Galindo, Danielle; Villanueva, Linda; Nguyen, Cathy; Patel, Milan; Borbridge, Lisa; Attar, Mayssa; Schiffman, Rhett M; Hollander, David A

Waterbury, L David; Galindo, Danielle; Villanueva, Linda; Nguyen, Cathy; Patel, Milan; Borbridge, Lisa; Attar, Mayssa; Schiffman, Rhett M; Hollander, David A.

Affiliation

Waterbury LD; Raven Biosolutions LLC, San Carlos, CA 94070, USA. david_waterbury@yahoo.com

J Ocul Pharmacol Ther ; 27(2): 173-8, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21351868

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Benzophenones/pharmacology; Bromobenzenes/pharmacology; Endophthalmitis/drug therapy; Eye/metabolism; Ketorolac/pharmacology; Animals; Aqueous Humor/drug effects; Aqueous Humor/metabolism; Benzophenones/pharmacokinetics; Bromobenzenes/pharmacokinetics; Dextrans/metabolism; Dinoprostone/analysis; Female; Fluorescein-5-isothiocyanate/analogs & derivatives; Fluorescein-5-isothiocyanate/metabolism; Ketorolac/pharmacokinetics; Lipopolysaccharides; Prostaglandin-Endoperoxide Synthases/metabolism; Rabbits

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzophenones / Bromobenzenes / Anti-Inflammatory Agents, Non-Steroidal / Endophthalmitis / Ketorolac / Eye Limits: Animals Language: En Journal: J Ocul Pharmacol Ther Journal subject: FARMACOLOGIA / OFTALMOLOGIA / TERAPEUTICA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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