Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells.

Pandit, Bulbul; Gartel, Andrei L

Pandit, Bulbul; Gartel, Andrei L.

Affiliation

Pandit B; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America.

PLoS One ; 6(2): e17110, 2011 Feb 18.

Article in En | MEDLINE | ID: mdl-21365012

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Apoptosis/drug effects; Boronic Acids/administration & dosage; Neoplasms/drug therapy; Pyrazines/administration & dosage; Thiostrepton/pharmacology; Antibiotics, Antineoplastic/administration & dosage; Antibiotics, Antineoplastic/pharmacology; Bortezomib; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; HCT116 Cells; Humans; Neoplasms/pathology; Thiazoles/administration & dosage; Thiazoles/pharmacology; Thiostrepton/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Thiostrepton / Boronic Acids / Antineoplastic Combined Chemotherapy Protocols / Apoptosis / Neoplasms Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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