Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl after sequential treatment with cyproterone acetate and testosterone propionate.

Bosland, M C; Prinsen, M K

Bosland, M C; Prinsen, M K.

Affiliation

Bosland MC; Department of Biological Toxicology, TNO-CIVO Toxicology and Nutrition Institute, Zeist, The Netherlands.

Cancer Res ; 50(3): 691-9, 1990 Feb 01.

Article in En | MEDLINE | ID: mdl-2137026

Subject(s)

9,10-Dimethyl-1,2-benzanthracene/administration & dosage; Adenocarcinoma/chemically induced; Aminobiphenyl Compounds/administration & dosage; Cyproterone/analogs & derivatives; Methylnitrosourea/administration & dosage; Prostatic Neoplasms/chemically induced; Testosterone/administration & dosage; Animals; Body Weight/drug effects; Cyproterone/administration & dosage; Cyproterone Acetate; Genitalia, Male/anatomy & histology; Male; Rats; Rats, Inbred Strains; Sarcoma, Experimental/chemically induced; Survival Analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Testosterone / Adenocarcinoma / Cyproterone / 9,10-Dimethyl-1,2-benzanthracene / Aminobiphenyl Compounds / Methylnitrosourea Limits: Animals Language: En Journal: Cancer Res Year: 1990 Document type: Article Affiliation country: Netherlands Country of publication: United States

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