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Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism.
De Serres, Mark; Bowers, Gary; Boyle, Gary; Beaumont, Claire; Castellino, Steve; Sigafoos, James; Dave, Mehul; Roberts, Andrew; Shah, Vishal; Olson, Katie; Patel, Dipak; Wagner, David; Yeager, Russell; Serabjit-Singh, Cosette.
Affiliation
  • De Serres M; Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, NC 27709, USA. mark.m.deserres@gsk.com
Xenobiotica ; 41(6): 464-75, 2011 Jun.
Article in En | MEDLINE | ID: mdl-21370990
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Chimera / Liver / Models, Biological Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Xenobiotica Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Chimera / Liver / Models, Biological Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Xenobiotica Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom