Synthesis and biological evaluation of a diazepanone-based library of liposidomycins analogs as MraY inhibitors.

Mravljak, Janez; Monasson, Olivier; Al-Dabbagh, Bayan; Crouvoisier, Muriel; Bouhss, Ahmed; Gravier-Pelletier, Christine; Le Merrer, Yves

Mravljak, Janez; Monasson, Olivier; Al-Dabbagh, Bayan; Crouvoisier, Muriel; Bouhss, Ahmed; Gravier-Pelletier, Christine; Le Merrer, Yves.

Affiliation

Mravljak J; Université Paris Descartes, UMR 8601 CNRS, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, 45 rue des Saints-Pères, 75006 Paris, France.

Eur J Med Chem ; 46(5): 1582-92, 2011 May.

Article in En | MEDLINE | ID: mdl-21377772

Subject(s)

Aminoglycosides/pharmacology; Azepines/chemistry; Bacterial Proteins/antagonists & inhibitors; Enzyme Inhibitors/chemical synthesis; Transferases/antagonists & inhibitors; Aminoglycosides/chemical synthesis; Aminoglycosides/chemistry; Dose-Response Relationship, Drug; Enzyme Inhibitors/chemistry; Enzyme Inhibitors/pharmacology; Molecular Structure; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship; Transferases (Other Substituted Phosphate Groups)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Bacterial Proteins / Transferases / Enzyme Inhibitors / Aminoglycosides Language: En Journal: Eur J Med Chem Year: 2011 Document type: Article Affiliation country: France Country of publication: France

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