Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

Dhawan, P; Ahmad, R; Chaturvedi, R; Smith, J J; Midha, R; Mittal, M K; Krishnan, M; Chen, X; Eschrich, S; Yeatman, T J; Harris, R C; Washington, M K; Wilson, K T; Beauchamp, R D; Singh, A B

Dhawan, P; Ahmad, R; Chaturvedi, R; Smith, J J; Midha, R; Mittal, M K; Krishnan, M; Chen, X; Eschrich, S; Yeatman, T J; Harris, R C; Washington, M K; Wilson, K T; Beauchamp, R D; Singh, A B.

Affiliation

Dhawan P; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Oncogene ; 30(29): 3234-47, 2011 Jul 21.

Article in En | MEDLINE | ID: mdl-21383692

Subject(s)

Colonic Neoplasms/genetics; ErbB Receptors/genetics; Membrane Proteins/metabolism; Transcriptional Activation; Animals; Caco-2 Cells; Cell Division/genetics; Claudins; Colonic Neoplasms/etiology; Colonic Neoplasms/pathology; Epidermal Growth Factor/pharmacology; Fluorouracil/pharmacology; Gene Expression Regulation, Neoplastic/drug effects; Gene Silencing; Humans; Inflammatory Bowel Diseases/etiology; Inflammatory Bowel Diseases/genetics; Inflammatory Bowel Diseases/pathology; Membrane Proteins/genetics; Mice; Mice, Nude; Protein Kinases/metabolism; RNA, Messenger/genetics; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcriptional Activation / Colonic Neoplasms / ErbB Receptors / Membrane Proteins Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom

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