Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+ channels.

Leiria, L O S; Mónica, F Z T; Carvalho, F D G F; Claudino, M A; Franco-Penteado, C F; Schenka, A; Grant, A D; De Nucci, G; Antunes, E

Leiria, L O S; Mónica, F Z T; Carvalho, F D G F; Claudino, M A; Franco-Penteado, C F; Schenka, A; Grant, A D; De Nucci, G; Antunes, E.

Affiliation

Leiria LO; Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil.

Br J Pharmacol ; 163(6): 1276-88, 2011 Jul.

Article in En | MEDLINE | ID: mdl-21391978

Subject(s)

Calcium Channels, L-Type/metabolism; Diabetes Mellitus, Experimental/complications; Urinary Bladder Diseases/etiology; Amides/pharmacology; Animals; Calcium Channel Blockers/pharmacology; Calcium Chloride/pharmacology; Carbachol/pharmacology; Cholinergic Agonists/pharmacology; Enzyme Inhibitors/pharmacology; Gene Expression Regulation/physiology; Male; Mice; Mice, Inbred C57BL; Nifedipine/pharmacology; Pyridines/pharmacology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptor, Muscarinic M2/genetics; Receptor, Muscarinic M2/metabolism; Receptor, Muscarinic M3/genetics; Receptor, Muscarinic M3/metabolism; Receptors, Purinergic P2X1/genetics; Receptors, Purinergic P2X1/metabolism; Urinary Bladder Diseases/pathology; rho-Associated Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Diseases / Calcium Channels, L-Type / Diabetes Mellitus, Experimental Limits: Animals Language: En Journal: Br J Pharmacol Year: 2011 Document type: Article Affiliation country: Brazil Country of publication: United kingdom

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