The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells.

Donati, G; Bertoni, S; Brighenti, E; Vici, M; Treré, D; Volarevic, S; Montanaro, L; Derenzini, M

Donati, G; Bertoni, S; Brighenti, E; Vici, M; Treré, D; Volarevic, S; Montanaro, L; Derenzini, M.

Affiliation

Donati G; Dipartimento di Patologia Sperimentale, Università di Bologna, Bologna, Italy.

Oncogene ; 30(29): 3274-88, 2011 Jul 21.

Article in En | MEDLINE | ID: mdl-21399665

Subject(s)

Down-Regulation; RNA, Ribosomal/biosynthesis; Ribosomal Proteins/biosynthesis; Tumor Suppressor Protein p53/metabolism; Up-Regulation; Animals; Cell Line, Tumor; Cell Nucleolus/metabolism; Gene Silencing; Humans; Hydrolysis; Proteasome Endopeptidase Complex/metabolism; RNA, Ribosomal/genetics; Rats; Ribosomal Proteins/genetics; Tumor Suppressor Protein p53/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribosomal Proteins / RNA, Ribosomal / Down-Regulation / Up-Regulation / Tumor Suppressor Protein p53 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2011 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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