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A changing trend in the management of patients with newly diagnosed Crohn's disease.
Qasim, A; Ullah, N; Crotty, P; Swan, N; Breslin, N; Ryan, B; Torreggiani, W; Eguare, E; Neary, P; O'Connor, H; O'Morain, C.
Affiliation
  • Qasim A; Adelaide and Meath Hospital, Tallaght/Trinity College, Dublin, Ireland. asgharqasim@yahoo.co.uk
Ir J Med Sci ; 180(3): 643-7, 2011 Sep.
Article in En | MEDLINE | ID: mdl-21431393
BACKGROUND: Epidemiologic shift with rising incidence of Crohn's disease (CD) has been reported in recent studies. AIMS: To determine disease behaviour and therapeutic interventions undertaken in newly diagnosed patients with CD. METHODS: Patients diagnosed with CD between January 2006 and June 2008 were included. Disease type, location, degree of involvement and type of therapeutic interventions were recorded. RESULTS: A total of 78 patients were included. Colonic, ileo-colonic, terminal ileal and isolated small bowel disease were present in 37, 27, 9 and 5 patients, respectively. Disease phenotype was inflammatory, stenosing and fistulising in 42, 30 and 6 patients, respectively. Surgery was required in 22 patients, including right hemicolectomy (n = 8), subtotal colectomy (n = 4), segmental colonic resection (n = 2), segmental small bowel resection (n = 2), appendectomy (n = 2) and perianal surgery (n = 4). Fourteen patients underwent surgery at the time of diagnosis. Laparoscopic surgery was performed in 14 patients. CONCLUSIONS: A significant proportion of newly diagnosed patients with CD underwent surgical intervention on their first admission to hospital. This may signify a changing trend in the management approach.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Crohn Disease / Colectomy Type of study: Diagnostic_studies / Incidence_studies / Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ir J Med Sci Year: 2011 Document type: Article Affiliation country: Ireland Country of publication: Ireland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Crohn Disease / Colectomy Type of study: Diagnostic_studies / Incidence_studies / Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ir J Med Sci Year: 2011 Document type: Article Affiliation country: Ireland Country of publication: Ireland