MCP-1-activated monocytes induce apoptosis in human retinal pigment epithelium.

Yang, Dongli; Elner, Susan G; Chen, Xun; Field, Matthew G; Petty, Howard R; Elner, Victor M

Yang, Dongli; Elner, Susan G; Chen, Xun; Field, Matthew G; Petty, Howard R; Elner, Victor M.

Affiliation

Yang D; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan 48105-0714, USA.

Invest Ophthalmol Vis Sci ; 52(8): 6026-34, 2011 Jul 29.

Article in En | MEDLINE | ID: mdl-21447688

Subject(s)

Apoptosis/immunology; Chemokine CCL2/immunology; Macular Degeneration/immunology; Monocytes/immunology; Retinal Pigment Epithelium/immunology; Aged; Aged, 80 and over; Antibodies/pharmacology; Apoptosis/drug effects; Calcium/metabolism; Calcium Signaling/physiology; Cells, Cultured; Chemokine CCL2/metabolism; Cyclic ADP-Ribose/analogs & derivatives; Cyclic ADP-Ribose/antagonists & inhibitors; Cyclic ADP-Ribose/pharmacology; Humans; Lipopolysaccharide Receptors/immunology; Macular Degeneration/pathology; Middle Aged; Monocytes/pathology; Reactive Oxygen Species/antagonists & inhibitors; Reactive Oxygen Species/metabolism; Retinal Pigment Epithelium/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Apoptosis / Chemokine CCL2 / Retinal Pigment Epithelium / Macular Degeneration Limits: Aged / Aged80 / Humans / Middle aged Language: En Journal: Invest Ophthalmol Vis Sci Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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