Diphenylamine-based retinoid antagonists: regulation of RAR and RXR function depending on the N-substituent.

Ohta, Kiminori; Kawachi, Emiko; Fukasawa, Hiroshi; Shudo, Koichi; Kagechika, Hiroyuki

Ohta, Kiminori; Kawachi, Emiko; Fukasawa, Hiroshi; Shudo, Koichi; Kagechika, Hiroyuki.

Affiliation

Ohta K; Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Aoba-ku, Sendai, Japan.

Bioorg Med Chem ; 19(8): 2501-7, 2011 Apr 15.

Article in En | MEDLINE | ID: mdl-21459577

Subject(s)

Diphenylamine/chemistry; Receptors, Retinoic Acid/drug effects; Retinoid X Receptors/drug effects; Retinoids/chemistry; Cell Differentiation/drug effects; Diphenylamine/pharmacology; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Receptors, Retinoic Acid/agonists; Receptors, Retinoic Acid/antagonists & inhibitors; Retinoid X Receptors/agonists; Retinoid X Receptors/antagonists & inhibitors; Retinoids/pharmacology; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinoids / Receptors, Retinoic Acid / Retinoid X Receptors / Diphenylamine Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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