Recombinant antibody libraries and selection technologies.
N Biotechnol
; 28(5): 448-52, 2011 Sep.
Article
in En
| MEDLINE
| ID: mdl-21477669
ABSTRACT
Active immunization has benefited human health perhaps more than any other biomedical advancement. Today, passive immunization is profoundly changing the practice of medicine by enabling antibody targeting of toxic, self, and other antigens not conducive to active immunization. Recombinant antibody libraries have contributed greatly to this progress and will continue to do so. The ability to construct and display a variety of antibody libraries, including naive, immune, semi-synthetic, and synthetic ones coupled with rapid screening and selection technologies, is in large measure responsible for the thousands of monoclonal antibody therapeutics in development.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Gene Library
/
Antibodies
Limits:
Animals
/
Humans
Language:
En
Journal:
N Biotechnol
Journal subject:
BIOLOGIA MOLECULAR
/
ENGENHARIA BIOMEDICA
Year:
2011
Document type:
Article
Affiliation country:
United States