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Global left atrial strain correlates with CHADS2 risk score in patients with atrial fibrillation.
Saha, Samir K; Anderson, Paula L; Caracciolo, Giuseppe; Kiotsekoglou, Anatoli; Wilansky, Susan; Govind, Satish; Mori, Naoyo; Sengupta, Partho P.
Affiliation
  • Saha SK; Department of Clinical Physiology, Cardiac and Vascular Sciences, Sundsvall Hospital and Karolinska Institute, Stockholm, Sweden.
J Am Soc Echocardiogr ; 24(5): 506-12, 2011 May.
Article in En | MEDLINE | ID: mdl-21477990
ABSTRACT

BACKGROUND:

The aim of this cross-sectional study was to explore the association between echocardiographic parameters and CHADS2 score in patients with nonvalvular atrial fibrillation (AF).

METHODS:

Seventy-seven subjects (36 patients with AF, 41 control subjects) underwent standard two-dimensional, Doppler, and speckle-tracking echocardiography to compute regional and global left atrial (LA) strain.

RESULTS:

Global longitudinal LA strain was reduced in patients with AF compared with controls (P < .001) and was a predictor of high risk for thromboembolism (CHADS2 score ≥ 2; odds ratio, 0.86; P = .02). LA strain indexes showed good interobserver and intraobserver variability. In sequential Cox models, the prediction of hospitalization and/or death was improved by addition of global LA strain and indexed LA volume to CHADS2 score (P = .003).

CONCLUSIONS:

LA strain is a reproducible marker of dynamic LA function and a predictor of stroke risk and cardiovascular outcomes in patients with AF.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Atrial Function, Left / Heart Atria Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Am Soc Echocardiogr Journal subject: DIAGNOSTICO POR IMAGEM Year: 2011 Document type: Article Affiliation country: Sweden

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Atrial Function, Left / Heart Atria Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Am Soc Echocardiogr Journal subject: DIAGNOSTICO POR IMAGEM Year: 2011 Document type: Article Affiliation country: Sweden