TCR transfer induces TCR-mediated tonic inhibition of RAG genes in human T cells.

Orlando, Luca; Accomasso, Lisa; Circosta, Paola; Turinetto, Valentina; Lantelme, Erica; Porcedda, Paola; Minieri, Valentina; Pautasso, Marisa; Willemsen, Ralph A; Cignetti, Alessandro; Giachino, Claudia

Orlando, Luca; Accomasso, Lisa; Circosta, Paola; Turinetto, Valentina; Lantelme, Erica; Porcedda, Paola; Minieri, Valentina; Pautasso, Marisa; Willemsen, Ralph A; Cignetti, Alessandro; Giachino, Claudia.

Affiliation

Orlando L; Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy. luca.orlando@unito.it

Mol Immunol ; 48(12-13): 1369-76, 2011 Jul.

Article in En | MEDLINE | ID: mdl-21481940

Subject(s)

DNA-Binding Proteins/genetics; Genes, RAG-1; Nuclear Proteins/genetics; Receptors, Antigen, T-Cell, alpha-beta/metabolism; Signal Transduction; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; Benzamides; Cell Line; Cell Membrane/immunology; Cell Membrane/metabolism; Child; DNA-Binding Proteins/metabolism; Dimethyl Sulfoxide/pharmacology; Down-Regulation; Flow Cytometry; Fluorescent Antibody Technique; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Humans; Imatinib Mesylate; Immunoblotting; Jurkat Cells; Ligands; Nuclear Proteins/metabolism; Piperazines/pharmacology; Pyrimidines/pharmacology; Receptors, Antigen, T-Cell, alpha-beta/genetics; Receptors, Antigen, T-Cell, alpha-beta/immunology; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus/pharmacology; Transduction, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / T-Lymphocytes / Signal Transduction / Receptors, Antigen, T-Cell, alpha-beta / Genes, RAG-1 / DNA-Binding Proteins Limits: Child / Humans Language: En Journal: Mol Immunol Year: 2011 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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