L-asparaginase treatment reduces the anticoagulant potential of the protein C system without affecting vitamin K-dependent carboxylation.

Vigano'D'Angelo, S; Gugliotta, L; Mattioli Belmonte, M; Cascione, M L; Pattarini, E; D'Angelo, A

Vigano'D'Angelo, S; Gugliotta, L; Mattioli Belmonte, M; Cascione, M L; Pattarini, E; D'Angelo, A.

Affiliation

Vigano'D'Angelo S; Servizio di Coagulazione, IRCCS H.S.Raffaele, Milano, Italy.

Thromb Res ; 59(6): 985-94, 1990 Sep 15.

Article in En | MEDLINE | ID: mdl-2148229

Subject(s)

Asparaginase/therapeutic use; Blood Coagulation/drug effects; Carbon-Carbon Ligases; Complement Inactivator Proteins; Ligases/drug effects; Protein C/antagonists & inhibitors; Adult; Amides/metabolism; Blood Coagulation Factors/drug effects; Blood Proteins/drug effects; Carrier Proteins/drug effects; Female; Glycoproteins/drug effects; Humans; Ligases/metabolism; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Protein S

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Collection: 01-internacional Database: MEDLINE Main subject: Asparaginase / Blood Coagulation / Complement Inactivator Proteins / Protein C / Carbon-Carbon Ligases / Ligases Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Thromb Res Year: 1990 Document type: Article Affiliation country: Italy Country of publication: United States

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