Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition.

Diness, Jonas G; Skibsbye, Lasse; Jespersen, Thomas; Bartels, Emil D; Sørensen, Ulrik S; Hansen, Rie S; Grunnet, Morten

Diness, Jonas G; Skibsbye, Lasse; Jespersen, Thomas; Bartels, Emil D; Sørensen, Ulrik S; Hansen, Rie S; Grunnet, Morten.

Affiliation

Diness JG; NeuroSearch A/S, Pederstrupvej 93, 2750 Ballerup, Denmark.

Hypertension ; 57(6): 1129-35, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21502564

Subject(s)

Atrial Fibrillation/prevention & control; Hypertension/physiopathology; Potassium Channel Blockers/pharmacology; Potassium Channels, Calcium-Activated/antagonists & inhibitors; 1-Naphthylamine/administration & dosage; 1-Naphthylamine/analogs & derivatives; 1-Naphthylamine/pharmacology; Age Factors; Alkanes/administration & dosage; Alkanes/pharmacology; Animals; Anti-Arrhythmia Agents/administration & dosage; Anti-Arrhythmia Agents/pharmacology; Atrial Fibrillation/physiopathology; Cardiac Pacing, Artificial; Disease Models, Animal; Humans; Injections, Intravenous; Male; Potassium Channel Blockers/administration & dosage; Potassium Channels, Calcium-Activated/physiology; Quinolinium Compounds/administration & dosage; Quinolinium Compounds/pharmacology; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Potassium Channels, Calcium-Activated / Potassium Channel Blockers / Hypertension Type of study: Clinical_trials / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Hypertension Year: 2011 Document type: Article Affiliation country: Denmark Country of publication: United States

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