Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models.

Sen, Arindam; Capitano, Maegan L; Spernyak, Joseph A; Schueckler, John T; Thomas, Seneca; Singh, Anurag K; Evans, Sharon S; Hylander, Bonnie L; Repasky, Elizabeth A

Sen, Arindam; Capitano, Maegan L; Spernyak, Joseph A; Schueckler, John T; Thomas, Seneca; Singh, Anurag K; Evans, Sharon S; Hylander, Bonnie L; Repasky, Elizabeth A.

Affiliation

Sen A; Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

Cancer Res ; 71(11): 3872-80, 2011 Jun 01.

Article in En | MEDLINE | ID: mdl-21512134

Subject(s)

Colonic Neoplasms/therapy; Hyperthermia, Induced/methods; Mammary Neoplasms, Experimental/therapy; Melanoma, Experimental/therapy; Animals; Body Temperature/physiology; Cell Hypoxia/physiology; Colonic Neoplasms/blood supply; Colonic Neoplasms/radiotherapy; Combined Modality Therapy; Disease Models, Animal; Extracellular Fluid/physiology; Female; Humans; Mammary Neoplasms, Experimental/blood supply; Mammary Neoplasms, Experimental/radiotherapy; Melanoma, Experimental/blood supply; Melanoma, Experimental/radiotherapy; Mice; Mice, Inbred BALB C

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Melanoma, Experimental / Colonic Neoplasms / Hyperthermia, Induced / Mammary Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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