Dengue vaccines: progress and challenges.
Curr Opin Immunol
; 23(3): 391-8, 2011 Jun.
Article
in En
| MEDLINE
| ID: mdl-21514129
ABSTRACT
With several dengue vaccine candidates progressing through clinical trials, several options for controlling this disease appear feasible. This would represent a major achievement and reflect decades of research and development activities. The challenges associated with the limited understanding of protective responses and those factors which determine disease severity remain, but with prospective studies ongoing in various dengue endemic areas and the initiation of dengue vaccine efficacy trials, immune responses are being evaluated in the context of protection and severe disease and these studies are highly likely to provide additional insights.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dengue
/
Dengue Vaccines
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Opin Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2011
Document type:
Article
Affiliation country:
United States
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM