Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade.

Hallett, William H D; Jing, Weiqing; Drobyski, William R; Johnson, Bryon D

Hallett, William H D; Jing, Weiqing; Drobyski, William R; Johnson, Bryon D.

Affiliation

Hallett WH; Department of Pediatrics, Division of Hematology/Oncology, Milwaukee, Wisconsin, USA.

Biol Blood Marrow Transplant ; 17(8): 1133-45, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21536144

Subject(s)

Antibodies, Monoclonal/pharmacology; B7-H1 Antigen/antagonists & inhibitors; Immunosuppressive Agents/pharmacology; Multiple Myeloma/immunology; Multiple Myeloma/therapy; Animals; Antibodies, Monoclonal/immunology; Apoptosis/immunology; B7-H1 Antigen/biosynthesis; B7-H1 Antigen/immunology; CD8-Positive T-Lymphocytes/immunology; Cell Line, Tumor; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hepatitis A Virus Cellular Receptor 2; Humans; Immunologic Memory; Immunosuppressive Agents/immunology; Killer Cells, Natural/immunology; Male; Mice; Mice, Inbred C57BL; Multiple Myeloma/pathology; Plasma Cells/immunology; Plasma Cells/pathology; Receptors, Virus/biosynthesis; Receptors, Virus/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B7-H1 Antigen / Immunosuppressive Agents / Antibodies, Monoclonal / Multiple Myeloma Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Biol Blood Marrow Transplant Journal subject: HEMATOLOGIA / TRANSPLANTE Year: 2011 Document type: Article Affiliation country: United States

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