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Stereotactic body radiation therapy: scope of the literature.
Tipton, Kelley; Launders, Jason H; Inamdar, Rohit; Miyamoto, Curtis; Schoelles, Karen.
Affiliation
  • Tipton K; ECRI Institute Evidence-based Practice Center, Plymouth Meeting, Pennsylvania 19462-1298, USA.
Ann Intern Med ; 154(11): 737-45, 2011 Jun 07.
Article in En | MEDLINE | ID: mdl-21536933
Stereotactic body radiation therapy (SBRT) is derived from the techniques of stereotactic radiosurgery used to treat lesions in the brain and spine. It combines multiple finely collimated radiation beams and stereotaxy to deliver a high dose of radiation to an extracranial target in the body in a single dose or a few fractions. This review provides a broad overview of the current state of SBRT for solid malignant tumors. Reviewers identified a total of 124 relevant studies. To our knowledge, no published comparative studies address the relative effectiveness and safety of SBRT versus other forms of external-beam radiation therapy. Stereotactic body radiation therapy seems to be widely diffused as a treatment of various types of cancer, although most studies have focused only on its use for treating thoracic tumors. Comparative studies are needed to provide evidence that the theoretical advantages of SBRT over other radiation therapies actually occur in the clinical setting; this area is currently being studied in only 1 small trial.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiosurgery / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Ann Intern Med Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiosurgery / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Ann Intern Med Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States