Development and validation of a quantitative assay for the determination of tamoxifen and its five main phase I metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry.

Teunissen, S F; Jager, N G L; Rosing, H; Schinkel, A H; Schellens, J H M; Beijnen, J H

Teunissen, S F; Jager, N G L; Rosing, H; Schinkel, A H; Schellens, J H M; Beijnen, J H.

Affiliation

Teunissen SF; Department of Pharmacy & Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands. Bas.Teunissen@slz.nl

J Chromatogr B Analyt Technol Biomed Life Sci ; 879(19): 1677-85, 2011 Jun 01.

Article in En | MEDLINE | ID: mdl-21543272

Subject(s)

Chromatography, Reverse-Phase/methods; Tamoxifen/analogs & derivatives; Tamoxifen/blood; Tandem Mass Spectrometry/methods; Drug Stability; Humans; Least-Squares Analysis; Reproducibility of Results; Sensitivity and Specificity; Tamoxifen/chemistry; Tamoxifen/isolation & purification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Tandem Mass Spectrometry / Chromatography, Reverse-Phase Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2011 Document type: Article Affiliation country: Netherlands Country of publication: Netherlands

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