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Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty.
Johnson, Stephanie R; Nolan, Richard C; Grant, Maree T; Price, Glynis J; Siafarikas, Aris; Bint, Lewis; Choong, Catherine Sy.
Affiliation
  • Johnson SR; Department of Endocrinology, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia. stephanie.johnson@health.wa.gov.au
J Paediatr Child Health ; 48(3): E136-9, 2012 Mar.
Article in En | MEDLINE | ID: mdl-21564386
ABSTRACT
We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as a result of which she developed sterile abscesses. She was converted to daily subcutaneous Leuprorelin acetate therapy with no recurrence of the abscesses. The possible mechanisms for this reaction are described in the article.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Puberty, Precocious / Leuprolide / Abscess Type of study: Diagnostic_studies / Risk_factors_studies Limits: Child / Female / Humans Language: En Journal: J Paediatr Child Health Journal subject: PEDIATRIA Year: 2012 Document type: Article Affiliation country: Australia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Puberty, Precocious / Leuprolide / Abscess Type of study: Diagnostic_studies / Risk_factors_studies Limits: Child / Female / Humans Language: En Journal: J Paediatr Child Health Journal subject: PEDIATRIA Year: 2012 Document type: Article Affiliation country: Australia