Luteolin induced G2 phase cell cycle arrest and apoptosis on non-small cell lung cancer cells.

Cai, Xueting; Ye, Tingmei; Liu, Chao; Lu, Wuguang; Lu, Min; Zhang, Juan; Wang, Min; Cao, Peng

Cai, Xueting; Ye, Tingmei; Liu, Chao; Lu, Wuguang; Lu, Min; Zhang, Juan; Wang, Min; Cao, Peng.

Affiliation

Cai X; School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, Jiangsu, China.

Toxicol In Vitro ; 25(7): 1385-91, 2011 Oct.

Article in En | MEDLINE | ID: mdl-21601631

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Carcinoma, Non-Small-Cell Lung/drug therapy; G2 Phase Cell Cycle Checkpoints/drug effects; Lung Neoplasms/drug therapy; Luteolin/pharmacology; Antineoplastic Agents/chemistry; Bisbenzimidazole/pharmacology; CDC2 Protein Kinase; Carcinoma, Non-Small-Cell Lung/pathology; Cell Line, Tumor; Cyclin A; Cyclin B/metabolism; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Fluorescent Dyes/pharmacology; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/pathology; Luteolin/chemistry; Molecular Structure; Phosphorylation; Retinoblastoma Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Carcinoma, Non-Small-Cell Lung / Luteolin / G2 Phase Cell Cycle Checkpoints / Lung Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Toxicol In Vitro Journal subject: TOXICOLOGIA Year: 2011 Document type: Article Affiliation country: China Country of publication: United kingdom

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