The effects of Leu or Val residues on cell selectivity of &#945;-helical peptides.

Ma, Qing-Quan; Shan, An-Shan; Dong, Na; Cao, Yan-Ping; Lv, Yin-Feng; Wang, Liang

The effects of Leu or Val residues on cell selectivity of α-helical peptides.

Ma, Qing-Quan; Shan, An-Shan; Dong, Na; Cao, Yan-Ping; Lv, Yin-Feng; Wang, Liang.

Affiliation

Ma QQ; Institute of Animal Nutrition, Northeast Agricultural University, Harbin, P R China, 150030.

Protein Pept Lett ; 18(11): 1112-8, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21605058

Subject(s)

Anti-Infective Agents/chemistry; Anti-Infective Agents/metabolism; Drug Design; Leucine; Peptides/chemistry; Peptides/metabolism; Valine; Amino Acid Sequence; Animals; Anti-Infective Agents/pharmacology; Anti-Infective Agents/toxicity; Cell Membrane/drug effects; Cell Membrane/metabolism; Cell Survival/drug effects; Chlorocebus aethiops; Hemolysis/drug effects; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Potentials/drug effects; Molecular Sequence Data; Peptides/pharmacology; Peptides/toxicity; Protein Structure, Secondary; Structure-Activity Relationship; Substrate Specificity; Unilamellar Liposomes/metabolism; Vero Cells

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Valine / Drug Design / Leucine / Anti-Infective Agents Limits: Animals / Humans Language: En Journal: Protein Pept Lett Journal subject: BIOQUIMICA Year: 2011 Document type: Article

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