Altering the Ad5 packaging domain affects the maturation of the Ad particles.

Alba, Raul; Cots, Dan; Ostapchuk, Philomena; Bosch, Assumpcio; Hearing, Patrick; Chillon, Miguel

Alba, Raul; Cots, Dan; Ostapchuk, Philomena; Bosch, Assumpcio; Hearing, Patrick; Chillon, Miguel.

Affiliation

Alba R; Center of Animal Biotechnology and Gene Therapy (CBATEG), and Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.

PLoS One ; 6(5): e19564, 2011.

Article in En | MEDLINE | ID: mdl-21611162

Subject(s)

Adenoviridae/physiology; Virion/metabolism; Virus Assembly/physiology; Adenoviridae/genetics; Adenoviridae/pathogenicity; Adenoviridae/ultrastructure; Attachment Sites, Microbiological/genetics; Base Sequence; Blotting, Southern; Capsid/metabolism; Cell Extracts; Cell Nucleus/virology; DNA, Viral/genetics; Electrophoretic Mobility Shift Assay; Genetic Vectors/genetics; Genome, Viral/genetics; HEK293 Cells; Humans; Nuclear Proteins/metabolism; Protein Binding; Time Factors; Viral Proteins/metabolism; Virion/ultrastructure; Virus Internalization; Virus Replication

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virion / Adenoviridae / Virus Assembly Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: Spain Country of publication: United States

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