Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis.

Thomas, Thommey P; Goonewardena, Sascha N; Majoros, Istvan J; Kotlyar, Alina; Cao, Zhengyi; Leroueil, Pascale R; Baker, James R

Thomas, Thommey P; Goonewardena, Sascha N; Majoros, Istvan J; Kotlyar, Alina; Cao, Zhengyi; Leroueil, Pascale R; Baker, James R.

Affiliation

Thomas TP; Michigan Nanotechnology Institute for Medicine and Biological Sciences, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

Arthritis Rheum ; 63(9): 2671-80, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21618461

Subject(s)

Arthritis, Experimental/drug therapy; Drug Carriers; Folic Acid/therapeutic use; Macrophages/drug effects; Methotrexate/therapeutic use; Nanoparticles/therapeutic use; Animals; Arthritis, Experimental/chemically induced; Cell Line; Cells, Cultured; Folic Acid/administration & dosage; Methotrexate/administration & dosage; Mice; Nanoparticles/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Drug Carriers / Methotrexate / Nanoparticles / Folic Acid / Macrophages Limits: Animals Language: En Journal: Arthritis Rheum Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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