N-methyl-D-aspartate receptor antagonist MK-801 suppresses glial pro-inflammatory cytokine expression in morphine-tolerant rats.

Liu, Ching-Hang; Cherng, Chen-Hwan; Cherng, Chen-Hwen; Lin, Shinn-Long; Yeh, Chun-Chang; Wu, Ching-Tang; Tai, Yueh-Hua; Wong, Chih-Shung

Liu, Ching-Hang; Cherng, Chen-Hwan; Cherng, Chen-Hwen; Lin, Shinn-Long; Yeh, Chun-Chang; Wu, Ching-Tang; Tai, Yueh-Hua; Wong, Chih-Shung.

Affiliation

Liu CH; Taiwan International Graduate Program, Graduate Institute of Life Science, National Defense Medical Center and Academia Sinica, Taipei, Taiwan.

Pharmacol Biochem Behav ; 99(3): 371-80, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21624390

Subject(s)

Cytokines/antagonists & inhibitors; Cytokines/biosynthesis; Dizocilpine Maleate/pharmacology; Inflammation/pathology; Inflammation/prevention & control; Morphine/pharmacology; Neuroglia/pathology; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors; Animals; Down-Regulation/drug effects; Down-Regulation/physiology; Drug Tolerance/physiology; Inflammation/drug therapy; Interleukin-1beta/antagonists & inhibitors; Interleukin-1beta/biosynthesis; Interleukin-6/antagonists & inhibitors; Interleukin-6/biosynthesis; Male; Neuroglia/drug effects; Neuroglia/metabolism; Pain Measurement/drug effects; Pain Measurement/methods; Random Allocation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate/physiology; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Tumor Necrosis Factor-alpha/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neuroglia / Cytokines / Dizocilpine Maleate / Receptors, N-Methyl-D-Aspartate / Inflammation / Morphine Limits: Animals Language: En Journal: Pharmacol Biochem Behav Year: 2011 Document type: Article Affiliation country: Taiwan Country of publication: United States

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