DNA dynamics is likely to be a factor in the genomic nucleotide repeats expansions related to diseases.

Alexandrov, Boian S; Valtchinov, Vlad I; Alexandrov, Ludmil B; Gelev, Vladimir; Dagon, Yossi; Bock, Jonathan; Kohane, Isaac S; Rasmussen, Kim Ø; Bishop, Alan R; Usheva, Anny

Alexandrov, Boian S; Valtchinov, Vlad I; Alexandrov, Ludmil B; Gelev, Vladimir; Dagon, Yossi; Bock, Jonathan; Kohane, Isaac S; Rasmussen, Kim Ø; Bishop, Alan R; Usheva, Anny.

Affiliation

Alexandrov BS; Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.

PLoS One ; 6(5): e19800, 2011.

Article in En | MEDLINE | ID: mdl-21625483

Subject(s)

DNA/genetics; DNA/metabolism; Neoplasms/genetics; Transcription Factors/metabolism; Trinucleotide Repeats/genetics; Binding Sites; Computer Simulation; Electrophoretic Mobility Shift Assay; HeLa Cells; Humans; Markov Chains; Promoter Regions, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / DNA / Trinucleotide Repeats / Neoplasms Type of study: Health_economic_evaluation / Prognostic_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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