Optimization of a radiolabel DNA-binding assay in cultured mammalian cells.

Pohl, Cecilia Diaz; Priestley, Catherine C; O'Donovan, Mike; Bolcsfoldi, George; Fred, Charlotta

Pohl, Cecilia Diaz; Priestley, Catherine C; O'Donovan, Mike; Bolcsfoldi, George; Fred, Charlotta.

Affiliation

Pohl CD; Genetic Toxicology, Safety Assessment, AstraZeneca R&D, Södertälje SE-15185, Sweden. Cecilia.diaz-pohl@astrazeneca.con

Mutat Res ; 723(2): 134-41, 2011 Aug 16.

Article in En | MEDLINE | ID: mdl-21640194

Subject(s)

DNA Adducts/biosynthesis; DNA/isolation & purification; DNA/metabolism; Mutagenicity Tests/methods; Mutagens/metabolism; Animals; Biotransformation; Cell Line, Tumor; Isotope Labeling; Leukemia L5178; Mice; Nucleic Acid Denaturation; Protein Binding; Research Design

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / DNA Adducts / Mutagenicity Tests / Mutagens Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mutat Res Year: 2011 Document type: Article Affiliation country: Sweden Country of publication: Netherlands

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