The lumenal loop Met672-Pro707 of copper-transporting ATPase ATP7A binds metals and facilitates copper release from the intramembrane sites.

Barry, Amanda N; Otoikhian, Adenike; Bhatt, Sujata; Shinde, Ujwal; Tsivkovskii, Ruslan; Blackburn, Ninian J; Lutsenko, Svetlana

Barry, Amanda N; Otoikhian, Adenike; Bhatt, Sujata; Shinde, Ujwal; Tsivkovskii, Ruslan; Blackburn, Ninian J; Lutsenko, Svetlana.

Affiliation

Barry AN; From the Department of Physiology, Johns Hopkins University, Baltimore, Maryland 21205, USA.

J Biol Chem ; 286(30): 26585-94, 2011 Jul 29.

Article in En | MEDLINE | ID: mdl-21646353

Subject(s)

Adenosine Triphosphatases/metabolism; Cation Transport Proteins/metabolism; Copper/metabolism; Adenosine Triphosphatases/chemistry; Adenosine Triphosphatases/genetics; Adenosine Triphosphate/chemistry; Adenosine Triphosphate/genetics; Adenosine Triphosphate/metabolism; Binding Sites; Biological Transport/genetics; Cation Transport Proteins/chemistry; Cation Transport Proteins/genetics; Cell Line; Copper/chemistry; Copper-Transporting ATPases; Humans; Menkes Kinky Hair Syndrome/genetics; Menkes Kinky Hair Syndrome/metabolism; Mutation; Protein Binding; Protein Structure, Secondary; Silver/chemistry; Silver/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Triphosphatases / Copper / Cation Transport Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google