Analytical characterization of a novel degradation product in a PEGylated recombinant protein. | J Pharm Sci;100(11): 4607-16, 2011 Nov. | MEDLINE

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Analytical characterization of a novel degradation product in a PEGylated recombinant protein.

Zhang, Bing; Towers, Edward W; Poppe, Leszek; Cockrill, Steven L.

Affiliation

Zhang B; Analytical Sciences, Amgen, Inc., Longmont, Colorado 80503, USA.

J Pharm Sci ; 100(11): 4607-16, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21647888

Subject(s)

Polyethylene Glycols/chemistry; Recombinant Proteins/chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Peptide Mapping; Tandem Mass Spectrometry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Recombinant Proteins Language: En Journal: J Pharm Sci Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Recombinant Proteins Language: En Journal: J Pharm Sci Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States