Insecticide detoxification indicator strains as tools for enhancing chemical discovery screens.

Shah, Sheetal; Yarrow, Carol; Dunning, Rebecca; Cheek, Ben; Vass, Simon; Windass, John; Hadfield, Stephen

Shah, Sheetal; Yarrow, Carol; Dunning, Rebecca; Cheek, Ben; Vass, Simon; Windass, John; Hadfield, Stephen.

Affiliation

Shah S; Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire, UK. Sheetal.shah@syngenta.com

Pest Manag Sci ; 68(1): 38-48, 2012 Jan.

Article in En | MEDLINE | ID: mdl-21681918

Subject(s)

Drosophila melanogaster/metabolism; Drug Evaluation, Preclinical/methods; Insecticides/metabolism; Animals; Animals, Genetically Modified/genetics; Animals, Genetically Modified/metabolism; Biological Assay; Cytochrome P-450 Enzyme System/genetics; Cytochrome P-450 Enzyme System/metabolism; Drosophila Proteins/genetics; Drosophila Proteins/metabolism; Drosophila melanogaster/drug effects; Drosophila melanogaster/genetics; Drug Evaluation, Preclinical/instrumentation; Imidazoles/metabolism; Imidazoles/pharmacology; Insecticides/pharmacology; Neonicotinoids; Nitro Compounds/metabolism; Nitro Compounds/pharmacology; Pyrazoles/metabolism; Pyrazoles/pharmacology; Receptors, Cytoplasmic and Nuclear/genetics; Receptors, Cytoplasmic and Nuclear/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drosophila melanogaster / Drug Evaluation, Preclinical / Insecticides Type of study: Evaluation_studies Limits: Animals Language: En Journal: Pest Manag Sci Journal subject: TOXICOLOGIA Year: 2012 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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