Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.

Ke, Hangjun; Morrisey, Joanne M; Ganesan, Suresh M; Painter, Heather J; Mather, Michael W; Vaidya, Akhil B

Ke, Hangjun; Morrisey, Joanne M; Ganesan, Suresh M; Painter, Heather J; Mather, Michael W; Vaidya, Akhil B.

Affiliation

Ke H; Department of Microbiology and Immunology, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.

Eukaryot Cell ; 10(8): 1053-61, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21685321

Subject(s)

Mitochondria/metabolism; Plasmodium falciparum/physiology; Antimalarials/pharmacology; Atovaquone/pharmacology; Cells, Cultured; Dihydroorotate Dehydrogenase; Drug Resistance; Electron Transport; Fungal Proteins/antagonists & inhibitors; Fungal Proteins/genetics; Fungal Proteins/metabolism; Humans; Mitochondria/enzymology; Organisms, Genetically Modified; Oxidoreductases Acting on CH-CH Group Donors/antagonists & inhibitors; Oxidoreductases Acting on CH-CH Group Donors/genetics; Oxidoreductases Acting on CH-CH Group Donors/metabolism; Parasitemia/parasitology; Plasmodium falciparum/drug effects; Plasmodium falciparum/genetics; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Ubiquinone/analogs & derivatives; Ubiquinone/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Mitochondria Limits: Humans Language: En Journal: Eukaryot Cell Journal subject: BIOLOGIA MOLECULAR Year: 2011 Document type: Article Affiliation country: United States

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