Neuroprotective effects of 3&#945;-acetoxyeudesma-1,4(15),11(13)-trien-12,6&#945;-olide against dopamine-induced apoptosis in the human neuroblastoma SH-SY5Y cell line.

Koo, Uk; Nam, Kung-Woo; Ham, Ahrom; Lyu, Dahyun; Kim, Bora; Lee, Sung-Jin; Kim, Kyeong Ho; Oh, Ki-Bong; Mar, Woongchon; Shin, Jongheon

Neuroprotective effects of 3α-acetoxyeudesma-1,4(15),11(13)-trien-12,6α-olide against dopamine-induced apoptosis in the human neuroblastoma SH-SY5Y cell line.

Koo, Uk; Nam, Kung-Woo; Ham, Ahrom; Lyu, Dahyun; Kim, Bora; Lee, Sung-Jin; Kim, Kyeong Ho; Oh, Ki-Bong; Mar, Woongchon; Shin, Jongheon.

Affiliation

Koo U; Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.

Neurochem Res ; 36(11): 1991-2001, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21688047

Subject(s)

Apoptosis/drug effects; Neuroprotective Agents/pharmacology; Sesquiterpenes, Eudesmane/therapeutic use; Antioxidants/therapeutic use; Caspase 3/metabolism; Cell Line, Tumor; Dopamine/pharmacology; Humans; Laurus/chemistry; Monophenol Monooxygenase/antagonists & inhibitors; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2/metabolism; Reactive Oxygen Species/metabolism; alpha-Synuclein/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Neuroprotective Agents / Sesquiterpenes, Eudesmane Limits: Humans Language: En Journal: Neurochem Res Year: 2011 Document type: Article Country of publication: United States

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