Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death.

Sherwood, Thomas W; Lee, Kirsten G; Gormley, Matthew G; Askwith, Candice C

Sherwood, Thomas W; Lee, Kirsten G; Gormley, Matthew G; Askwith, Candice C.

Affiliation

Sherwood TW; Department of Neuroscience, The Ohio State University, Columbus, Ohio 43210, USA.

J Neurosci ; 31(26): 9723-34, 2011 Jun 29.

Article in En | MEDLINE | ID: mdl-21715637

Subject(s)

Acidosis/metabolism; Cell Death/physiology; Hippocampus/metabolism; Nerve Tissue Proteins/metabolism; Neurons/metabolism; Sodium Channels/metabolism; Acid Sensing Ion Channels; Acidosis/physiopathology; Analysis of Variance; Animals; Electrophysiology; Hippocampus/physiopathology; Mice; Xenopus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acidosis / Sodium Channels / Cell Death / Hippocampus / Nerve Tissue Proteins / Neurons Limits: Animals Language: En Journal: J Neurosci Year: 2011 Document type: Article Affiliation country: United States

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