Coherent Raman scanning fiber endoscopy.
Opt Lett
; 36(13): 2396-8, 2011 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-21725423
Coherent Raman scattering methods allow for label-free imaging of tissue with chemical contrast and high spatial and temporal resolution. However, their imaging depth in scattering tissue is limited to less than 1 mm, requiring the development of endoscopes to obtain images deep inside the body. Here, we describe a coherent Raman endoscope that provides stimulated Raman scattering images at seven frames per second using a miniaturized fiber scanner, a custom-designed objective lens, and an optimized scheme for collection of scattered light from the tissue. We characterize the system and demonstrate chemical selectivity in mouse tissue images.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spectrum Analysis, Raman
/
Endoscopy
Limits:
Animals
Language:
En
Journal:
Opt Lett
Year:
2011
Document type:
Article
Affiliation country:
United States
Country of publication:
United States