Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for Pax2 and Emx2.

Boualia, Sami K; Gaitan, Yaned; Murawski, Inga; Nadon, Robert; Gupta, Indra R; Bouchard, Maxime

Boualia, Sami K; Gaitan, Yaned; Murawski, Inga; Nadon, Robert; Gupta, Indra R; Bouchard, Maxime.

Affiliation

Boualia SK; Department of Biochemistry and Goodman Cancer Centre, McGill University, Montreal, Quebec, Canada.

PLoS One ; 6(6): e21529, 2011.

Article in En | MEDLINE | ID: mdl-21731775

Subject(s)

Heterozygote; Homeodomain Proteins/genetics; PAX2 Transcription Factor/genetics; Transcription Factors/genetics; Urinary Tract/abnormalities; Vesico-Ureteral Reflux/pathology; Animals; Animals, Newborn; Conserved Sequence; Embryo, Mammalian/abnormalities; Embryo, Mammalian/pathology; Genetic Testing; Homeodomain Proteins/metabolism; Humans; Kidney/abnormalities; Kidney/embryology; Kidney/pathology; Mice; PAX2 Transcription Factor/metabolism; Protein Binding; Regulatory Sequences, Nucleic Acid/genetics; Transcription Factors/metabolism; Transcription, Genetic; Ureter/abnormalities; Ureter/embryology; Ureter/pathology; Urinary Tract/embryology; Vesico-Ureteral Reflux/embryology; Wolffian Ducts/metabolism; Wolffian Ducts/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Urinary Tract / Vesico-Ureteral Reflux / Homeodomain Proteins / PAX2 Transcription Factor / Heterozygote Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: Canada Country of publication: United States

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