Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer.

Luo, Wen; Schork, Nicholas J; Marschke, Keith B; Ng, Shi-Chung; Hermann, Thomas W; Zhang, Jinkun; Sanders, Jennifer M; Tooker, Patricia; Malo, Nathalie; Zapala, Matthew A; Dziewanowska, Zofia E; Negro-Vilar, Andres; Meglasson, Martin D

Luo, Wen; Schork, Nicholas J; Marschke, Keith B; Ng, Shi-Chung; Hermann, Thomas W; Zhang, Jinkun; Sanders, Jennifer M; Tooker, Patricia; Malo, Nathalie; Zapala, Matthew A; Dziewanowska, Zofia E; Negro-Vilar, Andres; Meglasson, Martin D.

Affiliation

Luo W; Ligand Pharmaceuticals, 5003 Ruette De Mer, San Diego, CA 92130, USA. WenL888@hotmail.com

Anticancer Res ; 31(6): 2303-11, 2011 Jun.

Article in En | MEDLINE | ID: mdl-21737656

Subject(s)

Carcinoma, Non-Small-Cell Lung/blood; Hypertriglyceridemia/chemically induced; Hypertriglyceridemia/genetics; Lung Neoplasms/blood; Tetrahydronaphthalenes/adverse effects; Bexarotene; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/genetics; Case-Control Studies; Clinical Trials, Phase III as Topic; DNA/blood; DNA/genetics; Female; Genetic Predisposition to Disease; Humans; Hypertriglyceridemia/blood; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Male; Middle Aged; Polymorphism, Single Nucleotide; Tetrahydronaphthalenes/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Tetrahydronaphthalenes / Hypertriglyceridemia / Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Anticancer Res Year: 2011 Document type: Article Affiliation country: United States Country of publication: Greece

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