The role of platelet factor 4 in radiation-induced thrombocytopenia.

Lambert, Michele P; Xiao, Liqing; Nguyen, Yvonne; Kowalska, M Anna; Poncz, Mortimer

Lambert, Michele P; Xiao, Liqing; Nguyen, Yvonne; Kowalska, M Anna; Poncz, Mortimer.

Affiliation

Lambert MP; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. lambertm@email.chop.edu

Int J Radiat Oncol Biol Phys ; 80(5): 1533-40, 2011 Aug 01.

Article in En | MEDLINE | ID: mdl-21740995

Subject(s)

Blood Platelets/radiation effects; Megakaryocytes/radiation effects; Platelet Factor 4/physiology; Thrombocytopenia/etiology; Animals; Blood Platelets/cytology; Bone Marrow/radiation effects; Cell Survival/drug effects; Cell Survival/physiology; Cell Survival/radiation effects; Colony-Forming Units Assay/methods; Culture Media, Conditioned/radiation effects; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Megakaryocytes/cytology; Megakaryocytes/drug effects; Megakaryocytes/metabolism; Mice; Mice, Knockout; Mice, Transgenic; Platelet Count; Platelet Factor 4/antagonists & inhibitors; Receptors, LDL/antagonists & inhibitors; Thrombocytopenia/blood; Thrombocytopenia/drug therapy; Thrombopoiesis/drug effects; Thrombopoiesis/physiology; Thrombopoiesis/radiation effects; Thrombopoietin/pharmacology; Tumor Suppressor Proteins/antagonists & inhibitors

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombocytopenia / Blood Platelets / Platelet Factor 4 / Megakaryocytes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Int J Radiat Oncol Biol Phys Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google