ALK fusion gene positive lung cancer and 3 cases treated with an inhibitor for ALK kinase activity.

Kimura, Hideki; Nakajima, Takahiro; Takeuchi, Kengo; Soda, Manabu; Mano, Hiroyuki; Iizasa, Toshihiko; Matsui, Yukiko; Yoshino, Mitsuru; Shingyoji, Masato; Itakura, Meiji; Itami, Makiko; Ikebe, Dai; Yokoi, Sana; Kageyama, Hajime; Ohira, Miki; Nakagawara, Akira

Kimura, Hideki; Nakajima, Takahiro; Takeuchi, Kengo; Soda, Manabu; Mano, Hiroyuki; Iizasa, Toshihiko; Matsui, Yukiko; Yoshino, Mitsuru; Shingyoji, Masato; Itakura, Meiji; Itami, Makiko; Ikebe, Dai; Yokoi, Sana; Kageyama, Hajime; Ohira, Miki; Nakagawara, Akira.

Affiliation

Kimura H; Division of Thoracic Diseases, Chiba Cancer Center, Chiba, Japan. hkimura@chiba-cc.jp

Lung Cancer ; 75(1): 66-72, 2012 Jan.

Article in En | MEDLINE | ID: mdl-21757253

Subject(s)

Gene Fusion; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Protein Kinase Inhibitors/therapeutic use; Receptor Protein-Tyrosine Kinases/antagonists & inhibitors; Receptor Protein-Tyrosine Kinases/genetics; Adenocarcinoma/drug therapy; Adenocarcinoma/genetics; Adenocarcinoma/pathology; Adenocarcinoma of Lung; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/genetics; Carcinoma, Non-Small-Cell Lung/pathology; Cell Cycle Proteins/genetics; Female; Humans; Immunohistochemistry/methods; Kinesins/genetics; Lung Neoplasms/enzymology; Lung Neoplasms/pathology; Male; Microtubule-Associated Proteins/genetics; Middle Aged; Neoplasm Metastasis/drug therapy; Neoplasm Metastasis/genetics; Neoplasm Metastasis/pathology; Neoplasm Staging/methods; Oncogene Proteins, Fusion/genetics; Protein-Tyrosine Kinases/antagonists & inhibitors; Serine Endopeptidases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptor Protein-Tyrosine Kinases / Protein Kinase Inhibitors / Gene Fusion / Lung Neoplasms Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Lung Cancer Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: Japan Country of publication: Ireland

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