Modelling the distribution of cortical lesions in multiple sclerosis.
Mult Scler
; 18(2): 229-31, 2012 Feb.
Article
in En
| MEDLINE
| ID: mdl-21757533
ABSTRACT
Recent studies have shown the relevance of the cerebral grey matter involvement in multiple sclerosis (MS). Cortical lesions (CLs), detected by specific MRI sequences, are likely to become a new research outcome in MS studies. The aim of this study was to infer the optimal statistical model describing the distribution of CLs in patients with relapsing-remitting (RR)MS. The negative binomial model gave the best fit to the observed distribution of CLs in a group of 44 RRMS patients with one MRI scan of the brain. This observation has important implications for the statistical analysis of CLs in MS studies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Magnetic Resonance Imaging
/
Cerebral Cortex
/
Multiple Sclerosis, Relapsing-Remitting
/
Models, Neurological
Type of study:
Prognostic_studies
Limits:
Adult
/
Humans
/
Middle aged
Language:
En
Journal:
Mult Scler
Journal subject:
NEUROLOGIA
Year:
2012
Document type:
Article
Affiliation country:
Italy