Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury.

Fu, Panfeng; Murley, Jeffrey S; Grdina, David J; Birukova, Anna A; Birukov, Konstantin G

Fu, Panfeng; Murley, Jeffrey S; Grdina, David J; Birukova, Anna A; Birukov, Konstantin G.

Affiliation

Fu P; Section of Pulmonary and Critical Care, Lung Injury Center, Department of Medicine, University of Chicago, IL, USA.

Crit Care Med ; 39(12): 2711-21, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21765345

Subject(s)

Amifostine/therapeutic use; Free Radical Scavengers/therapeutic use; Ventilator-Induced Lung Injury/drug therapy; Animals; Antioxidants/metabolism; Cells, Cultured; Endothelium/drug effects; Endothelium/metabolism; Inflammation/drug therapy; Lung/cytology; Lung/drug effects; Lung/metabolism; Mice; Mice, Inbred C57BL; Oxidative Stress/drug effects; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Free Radical Scavengers / Amifostine / Ventilator-Induced Lung Injury Type of study: Prognostic_studies Limits: Animals Language: En Journal: Crit Care Med Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google