Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.

Balasubramanian, Sivaprakasam; Chew, Yap Ching; Eckert, Richard L

Balasubramanian, Sivaprakasam; Chew, Yap Ching; Eckert, Richard L.

Affiliation

Balasubramanian S; Department of Biochemistry and Molecular Biology University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Mol Pharmacol ; 80(5): 870-8, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21807989

Subject(s)

Proteasome Endopeptidase Complex/metabolism; Repressor Proteins/antagonists & inhibitors; Skin Neoplasms/metabolism; Thiocyanates/pharmacology; Base Sequence; Cell Cycle/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; DNA Primers; Humans; Isothiocyanates; Polycomb-Group Proteins; Real-Time Polymerase Chain Reaction; Skin Neoplasms/enzymology; Skin Neoplasms/pathology; Sulfoxides

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Skin Neoplasms / Thiocyanates / Proteasome Endopeptidase Complex Limits: Humans Language: En Journal: Mol Pharmacol Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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