Interferon-lambda and therapy for chronic hepatitis C virus infection.

Donnelly, Raymond P; Dickensheets, Harold; O'Brien, Thomas R

Donnelly, Raymond P; Dickensheets, Harold; O'Brien, Thomas R.

Affiliation

Donnelly RP; Division of Therapeutic Proteins, Center for Drug Evaluation & Research, Food and Drug Administration, Bethesda, MD 20892, USA. Raymond.Donnelly@fda.hhs.gov

Trends Immunol ; 32(9): 443-50, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21820962

Subject(s)

Hepacivirus/drug effects; Hepatitis C, Chronic; Immunotherapy/methods; Interleukins/immunology; Interleukins/pharmacology; Animals; Antiviral Agents/administration & dosage; Antiviral Agents/therapeutic use; Chromosomes, Human, Pair 19/chemistry; Chromosomes, Human, Pair 19/genetics; Chromosomes, Human, Pair 19/immunology; Drug Therapy, Combination; Gene Expression Regulation/immunology; Hepacivirus/immunology; Hepatitis C, Chronic/genetics; Hepatitis C, Chronic/immunology; Hepatitis C, Chronic/therapy; Hepatitis C, Chronic/virology; Humans; Interferon alpha-2; Interferon-alpha/administration & dosage; Interferon-alpha/therapeutic use; Interferons; Interleukins/chemistry; Interleukins/genetics; Mice; Polyethylene Glycols/administration & dosage; Polyethylene Glycols/therapeutic use; Polymorphism, Single Nucleotide; Promoter Regions, Genetic/immunology; Recombinant Proteins/administration & dosage; Recombinant Proteins/therapeutic use; Ribavirin/administration & dosage; Ribavirin/therapeutic use; Transcription Factors/immunology; Transcription Factors/metabolism; Treatment Outcome; Viral Load/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukins / Hepacivirus / Hepatitis C, Chronic / Immunotherapy Language: En Journal: Trends Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United kingdom

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