Neurotrophin-3 gene-modified Schwann cells promote TrkC gene-modified mesenchymal stem cells to differentiate into neuron-like cells in poly(lactic-acid-co-glycolic acid) multiple-channel conduit.

Zhang, Yan-qing; He, Liu-min; Xing, Bin; Zeng, Xiang; Zeng, Chen-guang; Zhang, Wei; Quan, Da-ping; Zeng, Yuan-shan

Zhang, Yan-qing; He, Liu-min; Xing, Bin; Zeng, Xiang; Zeng, Chen-guang; Zhang, Wei; Quan, Da-ping; Zeng, Yuan-shan.

Affiliation

Zhang YQ; Department of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

Cells Tissues Organs ; 195(4): 313-22, 2012.

Article in En | MEDLINE | ID: mdl-21828999

Subject(s)

Cell Differentiation/drug effects; Lactic Acid/pharmacology; Mesenchymal Stem Cells/cytology; Neurons/cytology; Neurotrophin 3/genetics; Polyglycolic Acid/pharmacology; Receptor, trkC/genetics; Schwann Cells/metabolism; Animals; Biomarkers/metabolism; Coculture Techniques; Gene Expression Regulation/drug effects; Green Fluorescent Proteins/metabolism; Mesenchymal Stem Cells/drug effects; Mesenchymal Stem Cells/metabolism; Microscopy, Electron, Scanning; Neural Stem Cells/cytology; Neural Stem Cells/drug effects; Neural Stem Cells/metabolism; Neurogenesis/drug effects; Neurons/drug effects; Neurons/metabolism; Neurotrophin 3/metabolism; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Receptor, trkC/metabolism; Schwann Cells/cytology; Schwann Cells/drug effects; Synapses/drug effects; Synapses/metabolism; Tissue Scaffolds

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyglycolic Acid / Schwann Cells / Cell Differentiation / Lactic Acid / Receptor, trkC / Neurotrophin 3 / Mesenchymal Stem Cells / Neurons Limits: Animals Language: En Journal: Cells Tissues Organs Journal subject: ANATOMIA Year: 2012 Document type: Article Affiliation country: China Country of publication: Switzerland

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