[Klinefelter syndrome: spermatogenesis and quality of gametes]. / Syndrome de Klinefelter : qualité des gamètes et spermatogenèse.
Gynecol Obstet Fertil
; 39(9): 525-8, 2011 Sep.
Article
in Fr
| MEDLINE
| ID: mdl-21835669
Klinefelter syndrome is defined by the presence of a supernumerary X chromosome in a phenotypic male. It is the most frequent gonosomic anomaly in infertile men with an incidence of 0.1 to 0.2% in newborn males. The presence of an additional X chromosome induces spermatogenic failure but when gametes are present, they are usually normal. The risk of transmission of the chromosomal anomaly remains low. In the literature, only one 47,XXY foetus resulting from more than a hundred births from fathers with Klinefelter syndrome, has been reported. One can estimate, that a TESE performed in half of the patients with non-mosaic 47,XXY will be positive and may enable IVF/ICSI to be achieved.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spermatogenesis
/
Spermatozoa
/
Klinefelter Syndrome
Limits:
Humans
/
Male
Language:
Fr
Journal:
Gynecol Obstet Fertil
Journal subject:
GINECOLOGIA
/
OBSTETRICIA
Year:
2011
Document type:
Article
Affiliation country:
France
Country of publication:
France