Efficacy of a vaccine that links viral epitopes to flagellin in protecting aged mice from influenza viral infection.

Leng, Jin; Stout-Delgado, Heather W; Kavita, Uma; Jacobs, Andrea; Tang, Jie; Du, Wei; Tussey, Lynda; Goldstein, Daniel R

Leng, Jin; Stout-Delgado, Heather W; Kavita, Uma; Jacobs, Andrea; Tang, Jie; Du, Wei; Tussey, Lynda; Goldstein, Daniel R.

Affiliation

Leng J; Department of Internal Medicine and Immunobiology, Yale University of Medicine, New Haven, CT, USA.

Vaccine ; 29(45): 8147-55, 2011 Oct 19.

Article in En | MEDLINE | ID: mdl-21854824

Subject(s)

Epitopes/immunology; Flagellin/immunology; Hemagglutinin Glycoproteins, Influenza Virus/immunology; Influenza Vaccines/immunology; Orthomyxoviridae Infections/prevention & control; Aging/immunology; Animals; Epitopes/genetics; Flagellin/genetics; Hemagglutinin Glycoproteins, Influenza Virus/genetics; Humans; Influenza Vaccines/administration & dosage; Influenza Vaccines/genetics; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections/mortality; Orthomyxoviridae Infections/pathology; Survival Analysis; Vaccines, Synthetic/administration & dosage; Vaccines, Synthetic/genetics; Vaccines, Synthetic/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza Vaccines / Orthomyxoviridae Infections / Hemagglutinin Glycoproteins, Influenza Virus / Flagellin / Epitopes Limits: Animals / Humans Language: En Journal: Vaccine Year: 2011 Document type: Article Affiliation country: United States Country of publication: Netherlands

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