Detrimental effects of divalproex on warfarin therapy following mechanical valve replacement.
J Card Surg
; 26(5): 492-4, 2011 Sep.
Article
in En
| MEDLINE
| ID: mdl-21859435
ABSTRACT
Drug interaction between Warfarin and psychiatric agents may have important therapeutic effects for patients undergoing cardiac surgery. We present a case of a patient in whom concurrent treatment with Warfarin and valproic acid resulted in supratherapeutic international normalized ratio values. A discussion of the possible mechanisms for this interaction as well as a review of interactions between Warfarin and other psychiatric medications is the subject of this case report.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Warfarin
/
Bipolar Disorder
/
Heart Valve Prosthesis
/
Valproic Acid
/
Mitral Valve Insufficiency
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
J Card Surg
Journal subject:
CARDIOLOGIA
Year:
2011
Document type:
Article
Affiliation country:
United States