Bioactive A-type proanthocyanidins from Cinnamomum cassia.
J Nat Prod
; 74(9): 1833-41, 2011 Sep 23.
Article
in En
| MEDLINE
| ID: mdl-21875098
ABSTRACT
Two trimeric proanthocyanidins, cinnamtannin B-1 (1) and cinnamtannin D-1 (2), have been isolated from the bark of Cinnamomum cassia along with the known tetramer parameritannin A-1 (3) and a previously unreported tetramer, named cassiatannin A (4). The structures of 1-4 were elucidated on the basis of 1D and 2D NMR, MS, and CD analyses and compared to the reported data. Proanthocyanidins (1-4) possess significant in vitro inhibitory activity against cyclooxygenase-2 (COX-2) at micromolar concentrations.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cinnamomum aromaticum
/
Proanthocyanidins
/
Cyclooxygenase 2 Inhibitors
Language:
En
Journal:
J Nat Prod
Year:
2011
Document type:
Article
Affiliation country:
United States