Extracellular acidification induces connective tissue growth factor production through proton-sensing receptor OGR1 in human airway smooth muscle cells.

Matsuzaki, Shinichi; Ishizuka, Tamotsu; Yamada, Hidenori; Kamide, Yosuke; Hisada, Takeshi; Ichimonji, Isao; Aoki, Haruka; Yatomi, Masakiyo; Komachi, Mayumi; Tsurumaki, Hiroaki; Ono, Akihiro; Koga, Yasuhiko; Dobashi, Kunio; Mogi, Chihiro; Sato, Koichi; Tomura, Hideaki; Mori, Masatomo; Okajima, Fumikazu

Matsuzaki, Shinichi; Ishizuka, Tamotsu; Yamada, Hidenori; Kamide, Yosuke; Hisada, Takeshi; Ichimonji, Isao; Aoki, Haruka; Yatomi, Masakiyo; Komachi, Mayumi; Tsurumaki, Hiroaki; Ono, Akihiro; Koga, Yasuhiko; Dobashi, Kunio; Mogi, Chihiro; Sato, Koichi; Tomura, Hideaki; Mori, Masatomo; Okajima, Fumikazu.

Affiliation

Matsuzaki S; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.

Biochem Biophys Res Commun ; 413(4): 499-503, 2011 Oct 07.

Article in En | MEDLINE | ID: mdl-21907704

Subject(s)

Airway Remodeling; Connective Tissue Growth Factor/biosynthesis; Lung/metabolism; Myocytes, Smooth Muscle/metabolism; Receptors, G-Protein-Coupled/metabolism; Acids/metabolism; Calcium/metabolism; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate/pharmacology; Lung/cytology; Peptides, Cyclic/pharmacology; Protons; RNA, Small Interfering/genetics; Receptors, G-Protein-Coupled/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Smooth Muscle / Receptors, G-Protein-Coupled / Connective Tissue Growth Factor / Airway Remodeling / Lung Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2011 Document type: Article Affiliation country: Japan

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